SubtiBank SubtiBank
yacF [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]
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yacF [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

putative tRNA-dihydrouridine synthase B
locus
BSU00810
pI
7.00
mw
36.00 kDa
function
tRNA maturation
product
putative tRNA-dihydrouridine synthase B
essential
no
synonyms
dusB, dus1

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]
  • [SW|Categories] containing this gene/protein

  • [SW|translation]
  • Gene

    Coordinates on the chromosome (coding sequence)
    87,634 -> 88,635

    The protein

    Catalyzed reaction/ biological activity

  • a uridine in tRNA NADPH H → a 5,6-dihydrouridine in tRNA NADP
  • Protein family

  • dus family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [SW|YfjN]
  • [SW|Cofactors]

  • FMN or FAD [Pubmed|21635694]
  • Structure

  • [PDB|1VHN] (from ''Thermotoga maritima'', 35% identity, 54% similarity) [Pubmed|15103641]
  • Expression and Regulation

    Operon

  • ''[protein|search|pabB]-[protein|search|pabA]-[protein|search|pabC]-[protein|search|sul]-[protein|search|folB]-[protein|search|folK]-[protein|search|yazB]-[protein|search|yacF]-[protein|search|lysS]'' [Pubmed|9084182]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|9084182]
  • Additional information

  • the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
  • References

  • 12884008,9084182,25902496