SubtiBank SubtiBank
ypbH [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]
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ypbH [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

putative adaptor protein for ClpC-ClpP
locus
BSU22970
pI
4.00
mw
22.00 kDa
function
unknown
product
putative adaptor protein
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]
  • [SW|Categories] containing this gene/protein

  • [SW|proteolysis]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,403,506 -> 2,404,090

    Phenotypes of a mutant

  • deletion reduces sporulation to 20%, overexpression abolishes sporulation [Pubmed|11914365]
  • The protein

    Paralogous protein(s)

  • [protein|search|MecA]
  • Structure

  • [http://www.proteopedia.org/wiki/index.php/3jto 3JTO] (C-terminal domain) [Pubmed|19801546]
  • [SW|Interactions]

  • [protein|search|YpbH]-[protein|search|ClpC] [Pubmed|11914365]
  • Expression and Regulation

    Regulation

  • low expression, enhanced in stat phase in LB or competence but not in sporulation medium [Pubmed|11914365]
  • Biological materials

    Mutant

  • MGNA-A415 (ypbH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/415 NBRP B. subtilis, Japan]
  • GP812 (spc), GP814 (spc) both available in the [SW|Stülke] lab
  • References

    Reviews

  • 19609260,23375660
  • Original Publications

  • 11914365,19801546