SubtiBank SubtiBank
ypbH
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ypbH

putative adaptor protein for [protein|86A2F2F65290F4471D6FD03B694821C66C180D8A|ClpC]-[protein|CB06A70DE7462CEB7AF5D8C28943C878DD56DE1A|ClpP]
locus
BSU_22970
pI
4.09
mw
22.01 kDa
protein length
194 aa Sequence Blast
gene length
585 bp Sequence Blast
function
unknown
product
putative adaptor protein
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]

    • Gene

    Coordinates
    2,403,506 → 2,404,090

    Phenotypes of a mutant

  • deletion reduces sporulation to 20%, overexpression abolishes sporulation [Pubmed|11914365]

    • The protein

    Protein family

  • mecA family (with [protein|331993A875907C10C77105FD8DDD86D4412CE405|MecA], according to UniProt)

    • Paralogous protein(s)

  • [protein|331993A875907C10C77105FD8DDD86D4412CE405|MecA]

    • Structure

  • [PDB|3JTO] (C-terminal domain) [Pubmed|19801546]

    • Expression and Regulation

    Operons

    genes
    [gene|CE1C46944E242006383BA77B2C4E09045CB3B93F|ypbH]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-A415 (ypbH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/415 NBRP B. subtilis, Japan]
  • GP812 (spc), GP814 (spc) both available in the [SW|Stülke] lab
  • BKE22970 (Δ[gene|CE1C46944E242006383BA77B2C4E09045CB3B93F|ypbH]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAACGTTCCCTCCTGCCT, downstream forward: _UP4_TAAGAATGCAACGGAAAACT
  • BKK22970 (Δ[gene|CE1C46944E242006383BA77B2C4E09045CB3B93F|ypbH]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAACGTTCCCTCCTGCCT, downstream forward: _UP4_TAAGAATGCAACGGAAAACT

    • two-hybrid system

  • ''B. pertussis'' adenylate cyclase-based bacterial two hybrid system ([SW|BACTH]), available in [SW|Jörg Stülke]'s lab

    • References

    Reviews

  • 19609260,23375660

    • Original Publications

  • 11914365,19801546