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opuCC [Mon Aug 31 2015 13:56:51 GMT+0200 (CEST)]
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opuCC [Mon Aug 31 2015 13:56:51 GMT+0200 (CEST)]

glycine betaine/carnitine/choline ABC transporter (binding protein)
locus
BSU33810
pI
5.00
mw
33.00 kDa
function
compatible solute transport
product
glycine betaine/carnitine/choline ABC transporter (binding protein)
essential
no
synonyms
yvbC

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.4|Uptake of compatible solutes for osmoprotection]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|coping with hyper-osmotic stress], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|OpcR regulon], [SW|RemA regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,468,253 -> 3,469,164

    The protein

    Paralogous protein(s)

  • [SW|OpuBC]
  • Structure

  • [PDB|3PPN] [Pubmed|21366542]
  • [SW|Localization]

  • associated to the membrane (via [SW|OpuCB]-[SW|OpuCD]) [Pubmed|10092453]
  • lipoprotein [Pubmed|10216873]
  • [SW|Interactions]

  • [SW|OpuCA]-([SW|OpuCB]-[SW|OpuCD])-[SW|OpuCC] [Pubmed|10092453]
  • Expression and Regulation

    Operon

  • ''[SW|opuCA]-[SW|opuCB]-[SW|opuCC]-[SW|opuCD]'' [Pubmed|10216873]
  • [SW|Sigma factor]

  • induced by salt stress [Pubmed|23960087,10216873]
  • repressed by choline ([protein|search|OpcR]) [Pubmed|23960087]
  • Regulatory mechanism

  • [protein|search|OpcR]: transcription repression [Pubmed|23960087]
  • [protein|search|RemA]: transcription activation [Pubmed|23646920]
  • References

  • 10092453,9925583,10216873,21296969,21366542,23960087,23646920