gntP [Mon Aug 31 2015 13:57:43 GMT+0200 (CEST)]

gluconate permease

locus: BSU40070

pI: 8.10

mw: 46.00 kDa

function: gluconate uptake

product: gluconate permease

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.3|Carbohydrate transporter]
• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.13|Utilization of gluconate]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|utilization of specific carbon sources], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|AbrB regulon], [SW|CcpA regulon], [SW|GntR regulon]

The protein

Protein family

• gntP permease family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|YojA]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|gntR]-[protein|search|gntK]-[protein|search|gntP]-[protein|search|gntZ]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10746760 PubMed1] [http://www.ncbi.nlm.nih.gov/sites/entrez/3020045 PubMed2]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|3020045]

Regulation

• induced by gluconate ([protein|search|GntR]) [Pubmed|3020045]
• repressed by glucose ([protein|search|CcpA]) [Pubmed|8370661]

Regulatory mechanism

• [protein|search|GntR]: transcription repression [Pubmed|3020045]
• [protein|search|CcpA]: transcription repression [Pubmed|10666464]
• [protein|search|AbrB]: transcription activation [Pubmed|20817675]

References

• 3011959,8288545,3037520,2537826,3020045,10746760,8370661,1659648,220817675