dgcK [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

diguanylate cyclase

locus: BSU09120

pI: 8.00

mw: 40.00 kDa

function: synthesis of c-di-GMP

product: diguanylate cyclase

essential: no

synonyms: yhcK

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.3|Metabolism of signalling nucleotides]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|membrane proteins], [SW|metabolism of signalling nucleotides]

Gene

Coordinates on the chromosome (coding sequence): 985,734 -> 986,813

The protein

Catalyzed reaction/ biological activity

• synthesis of c-di-GMP from two molecules of GTP [Pubmed|23893111]

[SW|Domains]

• contains a C-terminal [SW|GGDEF domain] [Pubmed|22821967]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Biological materials

Mutant

• GP848 (''[protein|search|yhcK]''::''ermC''), available in [SW|Jörg Stülke]'s lab

References

• 23893111,22821967,27116468