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21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.
processing of CCA-less tRNA precursors
categories[category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.4|RNases] → [category|SW 184.108.40.206|Endoribonucleases][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 220.127.116.11|tRNA modification and maturation][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
2,478,006 → 2,478,929
Phenotypes of a mutantessential [Pubmed|12682299]
Catalyzed reaction/ biological activityEndonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule (according to UniProt)3' end maturation of tmRNA [Pubmed|25402410]
Protein family[SW|RNase] Z family (single member, according to UniProt)
Structure[PDB|2FK6] (in complex with tRNA-Thr) [Pubmed|22940585], [PDB|1Y44]
Expression and Regulation
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labs[SW|Ciaran Condon], IBPC, Paris, France [http://www.ibpc.fr/UPR9073/condon/index_en.html Homepage]