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yxaM
similar to antibiotic resistance protein
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
4,101,166 → 4,102,365
The protein
Protein family
[SW|major facilitator superfamily] (according to UniProt)[SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|787BB72119DB1321A8281D7C46FED28CAEDBC97C|yxbB]-[gene|88B01CC87394AEE693A98574F9343EBF99F0D60E|yxbA]-[gene|A15368CD02487EBC1AF999FED34672E38167BCB2|yxnB]-[gene|9446D9C88CBBBC5A08495D8AA49A92A9F47F2C9B|asnH]-[gene|BF0E188249161B3CC24D223FDD48B820EBED8F55|yxaM]
description
[Pubmed|10746760]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|20185509], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [Pubmed|12618455], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon][protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|15101989], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]regulation
repressed by glucose (8-fold) [Pubmed|12850135]view in new tabBiological materials
Mutant
MGNA-B688 (yxaM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1687 NBRP B. subtilis, Japan]BKE39930 (Δ[gene|BF0E188249161B3CC24D223FDD48B820EBED8F55|yxaM]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCGGAAAACGAATAAAAGA, downstream forward: _UP4_TAAATGTTTTGTATCACAGTBKK39930 (Δ[gene|BF0E188249161B3CC24D223FDD48B820EBED8F55|yxaM]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCGGAAAACGAATAAAAGA, downstream forward: _UP4_TAAATGTTTTGTATCACAGTReferences
10746760,10498721,12618455,15101989