required for the formation of RecA DNA repair centers
function
DNA repair/ recombination
product
formation of RecA DNA repair centers
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination][category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins][SW|Categories] containing this gene/protein
[SW|DNA repair/ recombination]Gene
Coordinates on the chromosome (coding sequence)
28,867 -> 29,463
Phenotypes of a mutant
drastically reduced survival of mature dormant spores after exposure to ultrahigh vacuum desiccation and ionizing radiation that induce single strand (ss) DNA nicks and double-strand breaks (DSBs) [Pubmed|24285298]The protein
Catalyzed reaction/ biological activity
required for the formation of [protein|search|RecA] DNA repair centers (together with [protein|search|RecO]) [Pubmed|24891441]Protein family
recR family (according to Swiss-Prot)Structure
[PDB|2V1C] (the [protein|search|RecR]-[protein|search|RecO] complex from ''Deinococcus radiodurans'', [protein|search|RecR]: 52% identity, 78% similarity, [protein|search|RecO]: 30%/ 58%) [Pubmed|17581636][SW|Localization]
cytoplasm (homogeneous) [Pubmed|16479537][SW|Interactions]
[protein|search|RecR]-[protein|search|RecO], [protein|search|RecR]:[protein|search|RecO] molecular ratio of 2:1 (as judged from other bacteria such as ''E. coli'' and ''Deinococcus radiodurans'') [Pubmed|17581636]Expression and Regulation
Additional information
the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]References
Reviews
Original publications
12884008,17581636,16479537,24285298,24285298,24891441,9157236,9108290,8419343 
