SubtiBank SubtiBank
ywpB
An ordered knock out library of all non-essential genes in B. subtilis is now available at Addgene. Information on ordering a copy can be found here. See Koo et al. 2017 for details about library construction.

ywpB

?-hydroxyacyl-(acyl carrier protein) dehydratase
locus
BSU36370
pI
9.36
mw
14.63 kDa
protein length
132 aa Sequence Blast
gene length
396 bp Sequence Blast
function
fatty acid biosynthesis
product
β-hydroxyacyl-ACP dehydratase
essential
yes
ec
4.2.1.59
synonyms
fabZ

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.1|Biosynthesis of fatty acids]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • Gene

    Coordinates
    3,743,732 → 3,744,157

    Phenotypes of a mutant

  • essential [Pubmed|23109554]
  • The protein

    Protein family

  • FabZ subfamily (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|65506215AE58BF53C57599E566E4F78514DB45AA|YcsD]
  • Structure

  • [PDB|3D6X] (from ''Campylobacter jejuni'', 45% identity, 67% similarity) [Pubmed|19280690]
  • Biological materials

    Mutant

  • MGNA-B265 (ywpB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1264 NBRP B. subtilis, Japan]
  • References

  • 17919287,19280690