SubtiBank SubtiBank
ydhE
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ydhE

similar to macrolide glycosyltransferase
locus
BSU_05720
pI
5.09
mw
42.87 kDa
protein length
395 aa Sequence Blast
gene length
1188 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity]
  • Gene

    Coordinates
    618,095 → 619,282

    The protein

    Protein family

  • UDP-glycosyltransferase family (with [protein|02927D2CC9F44B99DB307DDFED2DD52DE2196120|YjiC] and [protein|6D808BC20ADB6CA789288D50CA816D6BEE22CFC3|YojK], according to UniProt)
  • Structure

  • [PDB|2IYA] (from Streptomyces antibioticus, 28% identity) [pubmed|17376874]
  • Expression and Regulation

    Operons

    genes
    [gene|BD82663B1BF2763D2D2DE710C2896E4155419324|ydhE]
    description
    [Pubmed|20639339]

    regulatory mechanism

  • [protein|49E70A20CC05DBE485953C0AE34E634EFB33C3B2|LiaR]: activation, weak, in [regulon|49E70A20CC05DBE485953C0AE34E634EFB33C3B2|LiaR regulon]
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    Biological materials

    Mutant

  • MGNA-C180 (ydhE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2178 NBRP B. subtilis, Japan]
  • BKE05720 (Δ[gene|BD82663B1BF2763D2D2DE710C2896E4155419324|ydhE]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE05720 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTAGACAACTCCCTCTC, downstream forward: _UP4_TAAGAAAAAGAACTCCCGTA
  • BKK05720 (Δ[gene|BD82663B1BF2763D2D2DE710C2896E4155419324|ydhE]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK05720 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTAGACAACTCCCTCTC, downstream forward: _UP4_TAAGAAAAAGAACTCCCGTA
  • References

  • 20639339,27130432,17376874,31786106