required for normal spore cortex and coat synthesis, inhibits the proteolytic activity of FtsH (adaptor protein)
function
spore cortex and coat synthesis
product
spore coat morphogenetic protein
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.1|Class I][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|sporulation proteins], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon], [SW|SpoIIID regulon]Gene
Phenotypes of a mutant
reduction of sporulation efficiency due to defects in spore coat and cortex assembly [Pubmed|22463703]The protein
Catalyzed reaction/ biological activity
anchors the basement layer of the spore coat to the surface of the developing spore [Pubmed|22463703][SW|Domains]
contains an amphipathic alpha-helixStructure
[PDB|2MVH][SW|Localization]
around the surface of the developing forespore [Pubmed|22463703]spore membrane, recognizes membrane curvature [Pubmed|19265022]spore coat (basement), localization depends on [SW|SpoIVA] [Pubmed|22171814][SW|Interactions]
[SW|SpoIVA]-[SW|SpoVM]-[SW|SpoVID] [Pubmed|19775244][SW|SpoVM]-[protein|search|FtsH] [Pubmed|10913836]Expression and Regulation
Operon
''spoVM'' [Pubmed|8231808][SW|Sigma factor]
[protein|search|SigE] [Pubmed|8231808,15699190]Regulation
expressed in mother cell during sporulation ([protein|search|SigE], [SW|SpoIIID]) [Pubmed|8231808,15699190,19265022]Regulatory mechanism
[SW|SpoIIID]: transcription activation [Pubmed|8231808]References
Reviews
Original publications
10913836,18820968,8231808,9922240,19265022,12562810,9287010,17427285,19775244,15699190,22463703,22171814,22882210,25625300,25825747,25854653 
