yerC

similar to Trp repressor of S. aureus

Locus: BSU_06580

Isoelectric point: 4.85

Molecular weight: 11.89 kDa

Protein length: 104 aa

Gene length: 315 bp

Function: unknown

Product: unknown

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factor/ other/ based on similarity

Gene

Coordinates: 716,431 → 716,745

Phenotypes of a mutant

• inactivation of yerC reduces sporulation efficiency to 10% that of wild type cells PubMed

The protein

Structure

• 3KOR (Trp repressor of Staphylococcus aureus, 67% identity)

Expression and Regulation

Operons

• Genes: yerB-yerC
  Description: PubMed

  Regulatory mechanism

  • Spo0A: activation, PubMed, in Spo0A regulon

  Regulation

  • expressed under conditions that trigger sporulation (Spo0A) PubMed

• Genes: yerA-yerB-yerC
  Description: PubMed

Biological materials

Mutant

• MGNA-A924 (yerC::erm), available at the NBRP B. subtilis, Japan
• BKE06580 (ΔyerC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GCGTAATTTATCGATTTGCA, downstream forward: _UP4_TAAAAAACCGCCCTGCCGTC
• BKK06580 (ΔyerC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GCGTAATTTATCGATTTGCA, downstream forward: _UP4_TAAAAAACCGCCCTGCCGTC

References

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