alsT [Mon Aug 31 2015 13:54:36 GMT+0200 (CEST)]

amino acid carrier protein

locus: BSU18120

pI: 9.39

mw: 50.00 kDa

function: amino acid uptake

product: amino acid carrier protein

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.1|Solute:sodium symporter family]
• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.3|Alanine or glycine cation symporter family]
• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.1|Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation]
• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.1|Utilization of glutamine/ glutamate]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|putative amino acid transporter], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|TnrA regulon]

The protein

Protein family

• sodium:alanine (SAF) symporter family (according to Swiss-Prot)

[SW|Localization]

• cell membrane (according to Swiss-Prot), membrane [Pubmed|18763711]

Expression and Regulation

Regulation

• repressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|search|TnrA]) [Pubmed|12823818]

Regulatory mechanism

• [protein|search|TnrA]: transcription repression [Pubmed|12823818]

Biological materials

Mutant

• GP1888 (tet) available in [SW|Jörg Stülke]'s lab

References

• 12823818,25755103,18763711