SubtiBank SubtiBank
yfkF
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yfkF

similar to multidrug-efflux transporter
locus
BSU_07910
pI
8.91
mw
42.53 kDa
protein length
391 aa Sequence Blast
gene length
1176 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.12|Other transporters]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    863,862 → 865,037

    The protein

    Protein family

  • [SW|major facilitator superfamily] (according to UniProt)
  • Structure

  • [PDB|3WDO] (from E. coli, corresponds to aa 233 ... 344, 26% identity) [pubmed|23950222]
  • [SW|Localization]

  • cell membrane (according to UniProt)
  • Expression and Regulation

    Operons

    genes
    [gene|B56B38A1CCC0A73FFD9F3F4C9942356E6D818D2D|yfkF]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-C347 (yfkF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2345 NBRP B. subtilis, Japan]
  • BKE07910 (Δ[gene|B56B38A1CCC0A73FFD9F3F4C9942356E6D818D2D|yfkF]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE07910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTGTCAGTTCTCCTTA, downstream forward: _UP4_TAATCAAAAAGCCTCCCGAC
  • BKK07910 (Δ[gene|B56B38A1CCC0A73FFD9F3F4C9942356E6D818D2D|yfkF]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK07910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTGTCAGTTCTCCTTA, downstream forward: _UP4_TAATCAAAAAGCCTCCCGAC
  • References

  • 26528249,23950222