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nos [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]
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nos [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

nitric-oxide synthase
locus
BSU07630
pI
5.00
mw
38.00 kDa
function
production of nitric oxide
product
nitric-oxide synthase
essential
no
synonyms
yflM

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.1|Biosynthesis of antibacterial compounds]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.15|Biosynthesis of antibacterial compounds]
  • [SW|Categories] containing this gene/protein

  • [SW|miscellaneous metabolic pathways], [SW|biosynthesis of antibacterial compounds]
  • Gene

    Coordinates on the chromosome (coding sequence)
    836,653 -> 837,744

    The protein

    Catalyzed reaction/ biological activity

  • NADPH-dependent oxidation of l-arginine into l-citrulline [Pubmed|25826316]
  • Protein family

  • Bacterial NOS oxygenase subfamily (according to Swiss-Prot)
  • [SW|Cofactors]

  • heme b [Pubmed|20006999]
  • NADPH [Pubmed|25826316]
  • FMN or FAD [Pubmed|21635694]
  • Structure

  • [PDB|2AMO] (loose dimer), [PDB|1M7V] (bound to tetrahydrofolate and arginine)
  • [SW|Interactions]

  • [protein|search|Nos]-[protein|search|YkuN] (electron transfer from to [protein|search|Nos]) [Pubmed|25194416]
  • Expression and Regulation

    Operon

  • ''[protein|search|nos]-[protein|search|yflK]'' (according to [http://dbtbs.hgc.jp/COG/prom/yflMK.html DBTBS])
  • Additional information

  • Note that the gene '[protein|search|yflL]' is located between '[protein|search|nos]' and '[protein|search|yflK]', but on the opposite strand.
  • References

    Reviews

  • 9818193
  • Original publications

  • 12220171,11856757,20006999,21599925,22119809,23943262,21310962,21921039,25194416,25826316,26062720