SubtiBank SubtiBank
rplM
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rplM

ribosomal protein
locus
BSU_01490
pI
10.18
mw
16.15 kDa
protein length
145 aa Sequence Blast
gene length
438 bp Sequence Blast
function
translation
product
ribosomal protein L13
essential
yes
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • Gene

    Coordinates
    153,842 → 154,279

    Phenotypes of a mutant

  • essential [Pubmed|23002217,12682299]
  • The protein

    Protein family

  • universal [SW|ribosomal protein] uL13 family (single member, according to UniProt)
  • Structure

  • [PDB|3J9W] (the [SW|ribosome]) [Pubmed|25903689]
  • Expression and Regulation

    Operons

    genes
    [gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, [pubmed|11948165], in [regulon|stringent response|stringent response]
  • regulation

  • [protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • likely autorepression of [gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI] expression upon binding of excess [protein|B495FFC63413D518138F8C2F3FBC894038C97E0E|RplM] to the untranslated region of the [gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI] mRNA [Pubmed|17616982]
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    genes
    [gene|84334531D66BE7524021C4B40C3FA05AAFE0D7A6|truA]-[gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, [Pubmed|11948165], in [regulon|stringent response|stringent response]
  • regulation

  • [protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • view in new tab

    References

  • 19653700,11948165,10781545,20830302,23002217,25903689,17616982