SubtiBank SubtiBank
rplM
An ordered knock out library of all non-essential genes in B. subtilis is now available at Addgene. Information on ordering a copy can be found here. See Koo et al. 2017 for details about library construction.

rplM

ribosomal protein
locus
BSU01490
pI
10.18
mw
16.15 kDa
protein length
145 aa Sequence Blast
gene length
435 bp Sequence Blast
function
translation
product
ribosomal protein L13
essential
yes
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • Gene

    Coordinates
    153,842 → 154,279

    Phenotypes of a mutant

  • essential [Pubmed|23002217,12682299]
  • The protein

    Protein family

  • [SW|ribosomal protein] L13P family (according to Swiss-Prot)
  • Structure

  • [PDB|3J9W] (the [SW|ribosome]) [Pubmed|25903689]
  • Expression and Regulation

    Operons

    genes
    [gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, [pubmed|11948165], in [regulon|stringent response|stringent response]
  • regulation

  • [protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
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    genes
    [gene|84334531D66BE7524021C4B40C3FA05AAFE0D7A6|truA]->[gene|B495FFC63413D518138F8C2F3FBC894038C97E0E|rplM]-[gene|C8E45EDBCD0CFF353D1D66E6D77FD81E976BC0BC|rpsI]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, [Pubmed|11948165], in [regulon|stringent response|stringent response]
  • regulation

  • [protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • view in new tab

    References

  • 19653700,11948165,10781545,20830302,23002217,25903689