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rbfA
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rbfA

ribosome-binding factor A
locus
BSU_16650
pI
9.34
mw
13.25 kDa
protein length
117 aa Sequence Blast
gene length
354 bp Sequence Blast
function
translation
product
ribosome-binding factor A
essential
no
synonyms
ymxE,ylxO
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.11|Translation factors]

    • Gene

    Coordinates
    1,736,451 → 1,736,804

    The protein

    Protein family

  • rbfA family (single member, according to UniProt)

    • Structure

  • [PDB|1JOS] (from ''Haemophilus influenzae'', 45% identity)

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|9F6C447900410BF64409E5C41A11C76968DADAFA|ylxS]-[gene|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|nusA]-[gene|F4097349A563503468A2A14F062AEAC532C7917A|ylxR]-[gene|7BFA65857F69855DBB3BB64D93B4ED2F09DC705B|rplGA]-[gene|378B77412D0DEA220A97DEC246410509D9B74D46|infB]-[gene|24835CE6CD2E1F183DB9121F29A63101718B5DF9|ylxP]-[gene|B3119A40393A288EF34FC3E9839B6E40AC6A6EA0|rbfA]
    description
    [Pubmed|8491709]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8491709], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528,26577401], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

    • regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]
  • [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA]: attenuation, [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA] stimulates termination [Reference|http://www.nature.com/articles/nmicrobiol20157], in [regulon|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA regulon]

    • regulation

  • autoregulation [SW|NusA] [http://www.nature.com/articles/nmicrobiol20157 reference]
  • induced by glucose [pubmed|30355672]
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    Biological materials

    Mutant

  • BKE16650 (Δ[gene|B3119A40393A288EF34FC3E9839B6E40AC6A6EA0|rbfA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACTCAATTCAATCACCT, downstream forward: _UP4_TAAAAAAAGAGAGGATAGGC
  • BKK16650 (Δ[gene|B3119A40393A288EF34FC3E9839B6E40AC6A6EA0|rbfA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACTCAATTCAATCACCT, downstream forward: _UP4_TAAAAAAAGAGAGGATAGGC

    • References

  • 8491709,11948165,26577401