ypuD

putative intramembrane metalloprotease

locus: BSU_23300

pI: 7.03

mw: 12.61 kDa

protein length: 114 aa

gene length: 345 bp

function: unknown

product: putative intramembrane metalloprotease

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]

Gene

Coordinates: 2,431,737 → 2,432,081

Expression and Regulation

Operons

• genes: [gene|B2DC4E57065C76E3A67D05BDDF53B7067345B94B|ypuD]
  description: [Pubmed|7934830]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|11544224], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • [protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon]

  regulatory mechanism

  • [protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [Pubmed|16267290], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]

  regulation

  • induced by DNA damage ([protein|search|LexA]) [Pubmed|16267290]

Biological materials

Mutant

• MGNA-A092 (ypuD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/92 NBRP B. subtilis, Japan]
• BKE23300 (Δ[gene|B2DC4E57065C76E3A67D05BDDF53B7067345B94B|ypuD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE23300 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTAAACCTCCAGCCA, downstream forward: _UP4_TAAAAAACATCACCTTTCGG
• BKK23300 (Δ[gene|B2DC4E57065C76E3A67D05BDDF53B7067345B94B|ypuD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK23300 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTAAACCTCCAGCCA, downstream forward: _UP4_TAAAAAACATCACCTTTCGG

References

Reviews

• 29343670

Original publications

• 16267290,11544224,7934830,18179421