phy [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

phytase

locus: BSU19800

pI: 4.94

mw: 41.00 kDa

function: untilization of inositol hexakisphosphate (phytate)

product: 3-phytase

essential: no

ec: 3.1.3.8

synonyms: yodV, yzxA

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.3|Phosphate metabolism]
• [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]

[SW|Categories] containing this gene/protein

• [SW|phosphate metabolism]

This gene is a member of the following [SW|regulons]

• [SW|AbrB regulon]

Gene

Coordinates on the chromosome (coding sequence): 2,150,108 -> 2,151,256

The protein

Catalyzed reaction/ biological activity

• Myo-inositol hexakisphosphate + H₂O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate (according to Swiss-Prot)

Protein family

• msrA Met sulfoxide reductase family (according to Swiss-Prot)

Structure

• [PDB|3AMR]

[SW|Localization]

• extracellular (signal peptide) [Pubmed|18957862]

Expression and Regulation

Operon

• ''phy'' [Pubmed|7592393]

[SW|Sigma factor]

• none [Pubmed|16980498]

Regulatory mechanism

• [protein|search|AbrB]: transcription repression [Pubmed|20817675]

Additional information

• the gene is not expressed in 'B. subtilis' due to the absene of a functional promoter [PubMed|16980498]

References

• 18957862,24407511,10655618,7592393,16980498,20601512,23178368,20817675,26106383