SubtiBank SubtiBank
yjcD
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yjcD

similar to ATP-dependent DNA helicase
locus
BSU_11820
pI
8.02
mw
86.79 kDa
protein length
717 aa Sequence Blast
gene length
2154 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.6|DNA repair/ recombination/ based on similarity]

    • Gene

    Coordinates
    1,253,713 → 1,255,866

    The protein

    Catalyzed reaction/ biological activity

  • ATP + H2O --> ADP + H+ + phosphate (according to UniProt)

    • Protein family

  • [SW|helicase family] (according to UniProt)

    • Paralogous protein(s)

  • [protein|C73E52D214E24F21696973B19B0A44CE785D6FBA|PcrA]

    • [SW|Domains]

  • [SW|UvrD-like helicase ATP-binding domain](aa 134-413) (according to UniProt)
  • [SW|UvrD-like helicase C-terminal domain] (aa 414-676) (according to UniProt)

    • Structure

  • [PDB|2PJR] ([protein|C73E52D214E24F21696973B19B0A44CE785D6FBA|PcrA] product complex, complex with sulphate ion, ''Geobacillus stearothermophilus'', 36% identity, 55% similarity)
  • [PDB|1PJR] ([protein|C73E52D214E24F21696973B19B0A44CE785D6FBA|PcrA] substrate complex, complex with DNA, ''Geobacillus stearothermophilus'', 36% identity, 55% similarity)

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|B0789A727D9E3578FF1CB6162F365F45FADB0B3E|yjcD]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-A159 (yjcD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/159 NBRP B. subtilis, Japan]
  • BKE11820 (Δ[gene|B0789A727D9E3578FF1CB6162F365F45FADB0B3E|yjcD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAACGGGCTTTCCGCAAT, downstream forward: _UP4_TAACAGCCCGGCAGATTACT
  • BKK11820 (Δ[gene|B0789A727D9E3578FF1CB6162F365F45FADB0B3E|yjcD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAACGGGCTTTCCGCAAT, downstream forward: _UP4_TAACAGCCCGGCAGATTACT

    • References

  • 10199404