SubtiBank SubtiBank
plsY
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plsY

acylphosphate:glycerol-phosphate acyltransferase
locus
BSU_18070
pI
10.41
mw
20.82 kDa
protein length
193 aa Sequence Blast
gene length
582 bp Sequence Blast
function
biosynthesis of phospholipids
product
acylphosphate:glycerol-phosphate acyltransferase
essential
yes
ec
2.3.1.n3
synonyms
yneS

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.2|Biosynthesis of phospholipids]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    1,931,920 1,932,501

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Catalyzed reaction/ biological activity

  • Acyl-phosphate + sn-glycerol 3-phosphate --> acyl-sn-glycerol 3-phosphate + phosphate (according to UniProt)
  • Protein family

  • PlsY family (single member, according to UniProt)
  • Structure

  • [PDB|5XJ5] (from Aquifex aeolicus, 39% identity) [pubmed|29167463]
  • [SW|Localization]

  • cell membrane [Pubmed|19820159]
  • Expression and Regulation

    Operons

    genes
    [gene|ADDEE0B251CBE61892482F15F91543242EDBF2A0|plsY]-[gene|5959516D55C9EDBFC46F28C8248D374832895740|yneR]
    description
    [Pubmed|22383849]
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    Biological materials

    two-hybrid system

  • ''B. pertussis'' adenylate cyclase-based bacterial two hybrid system ([SW|BACTH]), available in Matsumoto lab [Pubmed|19282621]
  • References

    Reviews

  • 15952903,17919287
  • Original Publications

  • 19282621,17005971,17557823,19820159,29167463