function
control of SigB activity
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue][SW|Categories] containing this gene/protein
[SW|sigma factors and their control], [SW|general stress proteins (controlled by SigB)], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|SigB regulon]Gene
Coordinates on the chromosome (coding sequence)
522,088 -> 522,417
The protein
Protein family
STAS domain (according to Swiss-Prot)Modification
phosphorylation on Ser-52 AND Ser-56 by [protein|search|RsbW] [Pubmed|17218307], [Pubmed|17726680]Structure
[PDB|1VC1] (homolog from Thermotoga maritima)[SW|Interactions]
[protein|search|RsbU]-[protein|search|RsbV] [Pubmed|10632888][protein|search|RsbP]-[protein|search|RsbV] [Pubmed|10632888][protein|search|RsbV]-[SW|SpoIIAB] [Pubmed|8764398][protein|search|RsbV]-[protein|search|RsbW][Pubmed|8144446]Expression and Regulation
Operon
''[protein|search|rsbR]-[protein|search|rsbS]-[protein|search|rsbT]-[protein|search|rsbU]-[protein|search|rsbV]-[protein|search|rsbW]-[protein|search|sigB]-[protein|search|rsbX]'' [Pubmed|8002610]''[protein|search|rsbV]-[protein|search|rsbW]-[protein|search|sigB]-[protein|search|rsbX]'' [Pubmed|2170324][SW|Sigma factor]
''[protein|search|rsbR]'': [protein|search|SigA] [Pubmed|8002610]''[protein|search|rsbV]:'' [protein|search|SigB] [Pubmed|11544224]Regulation
''[protein|search|rsbV]:'' induced by stress ([protein|search|SigB]) [Pubmed|11544224]''[protein|search|rsbV]:'' repressed by glucose ([protein|search|CcpA]) [Pubmed|20454630]Regulatory mechanism
CcpA: transcription repression [Pubmed|20454630]Labs working on this gene/protein
[SW|Bill Haldenwang], San Antonio, USA[SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]References
12867438,8144446,8002610,8682769,11591687,9658013,8682789,8955331,8764398,8824586,10632888,8808936,7601843,15342585,12270815,12950915,8955331,17726680,11544224,17218307,20454630 
