SubtiBank SubtiBank
yydA
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yydA

similar to pseudouridine methyltransferase
locus
BSU_40230
pI
9.31
mw
17.93 kDa
protein length
159 aa Sequence Blast
gene length
480 bp Sequence Blast
function
may be involved in maturation of 23S rRNA
product
similar to pseudouridine methyltransferase
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.3|rRNA modification and maturation/ based on similarity]
  • Gene

    Coordinates
    4,134,436 4,134,915

    The protein

    Catalyzed reaction/ biological activity

  • pseudouridine1915 in 23S rRNA + S-adenosyl-L-methionine --> H+ + N3-methylpseudouridine1915 in 23S rRNA + S-adenosyl-L-homocysteine (according to UniProt)
  • Protein family

  • RNA methyltransferase rlmH family (single member, according to UniProt)
  • Structure

  • [PDB|1TO0]
  • Expression and Regulation

    Operons

    genes
    [gene|AC2A9DC3DA569231442582A95EDB2A98BA335184|yydA]

    regulatory mechanism

  • [protein|6740108089F13116F200C15F35C2E7561E990FEB|DnaA]: repression, [Pubmed|17932079], in [regulon|6740108089F13116F200C15F35C2E7561E990FEB|DnaA regulon]
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    genes
    [gene|660FD9F2AC911E4E70E242F14A2EA6A208F25E28|yyzF]-[gene|AC2A9DC3DA569231442582A95EDB2A98BA335184|yydA]-[gene|F30AA652362B7459D479345AB373D19FA1EAFBBF|yydB]-[gene|235399FB29FA7443D41AA9543EEB18F195503091|yydC]-[gene|1470E1E1BAE5EA5BA9831E2BCEF9B61E79450510|yydD]
    description
    [pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-B814 (yydA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1813 NBRP B. subtilis, Japan]
  • References

  • 17932079,18755836,18755835,20817755