SubtiBank SubtiBank
lrpC
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lrpC

sequence-independent DNA-binding and DNA-bending protein (Lrp family), facilitates the formation of higher order protein-DNA complexes
locus
BSU_04250
pI
7.74
mw
16.31 kDa
protein length
144 aa Sequence Blast
gene length
435 bp Sequence Blast
function
DNA repair/ recombination
product
DNA-binding and -bending protein
essential
no
synonyms
ydaI

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
  • Gene

    Coordinates
    476,059 476,493

    The protein

    Protein family

  • ([SW|Lrp family])
  • [SW|Domains]

  • [SW|HTH asnC-type domain] (aa 3-64) (according to UniProt)
  • Structure

  • [PDB|2CFX] [pubmed|16528101]
  • Expression and Regulation

    Operons

    genes
    [gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]-[gene|7D5327BD1DD5FD5F90B2C849589923AA3D8B20EF|topB]

    description

  • [pubmed|22383849]
  • sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [pubmed|10913073], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
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    additional information

  • 50 ... 300 molecules per cell [PubMed|10913073]
  • Biological materials

    Mutant

  • MGNA-C106 (ydaI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2104 NBRP B. subtilis, Japan]
  • BKE04250 ([gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE04250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACATCCTTCTTTT, downstream forward: _UP4_TAGAGAGTGCCGCGCGAAGT
  • BKK04250 ([gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK04250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACATCCTTCTTTT, downstream forward: _UP4_TAGAGAGTGCCGCGCGAAGT
  • References

  • 9341680,10913073,16407330,10606655,12458218,16528101,16528101