cotT [Mon Aug 31 2015 13:53:44 GMT+0200 (CEST)]

spore coat protein (inner)

locus: BSU12090

pI: 9.47

mw: 12.00 kDa

function: resistance of the spore

product: spore coat protein (inner)

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.4|Class IV]

[SW|Categories] containing this gene/protein

• [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigK regulon], [SW|GerE regulon], [SW|SigE regulon], [SW|SpoIIID regulon]

The protein

[SW|Localization]

• inner spore coat, localization depends on [protein|search|SafA] [Pubmed|22171814,19933362]

Expression and Regulation

Operon

• ''cotT'' [Pubmed|2546006]

[SW|Sigma factor]

• [protein|search|SigK] [Pubmed|2546006,15699190,15383836], [protein|search|SigE] [Pubmed|15383836]

Regulation

• expressed during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE], [SW|SpoIIID]) [Pubmed|2546006,15699190,15383836]

Regulatory mechanism

• [SW|SpoIIID]: transcription activation [Pubmed|15383836]
• [protein|search|GerE]: transcription repression [Pubmed|15383836]

Biological materials

Mutant

• 1S108 ( ''cotT''::''cat''), [Pubmed|2546006], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S108&Search=1S108 BGSC]

Labs working on this gene/protein

• [SW|Arthur Aronson], Purdue University, West Lafayette, USA [http://wwwdev.gradschool.purdue.edu/PULSe/faculty.cfm?fid=5&range=0 homepage]

References

Reviews

• 23202530

Original publications

• 10714992,1917883,2546006,15699190,15383836,19933362,22171814