adeR [2017-8-11 16:0:3]

transcription activator (PucR family) for ald gene expression

locus: BSU31920

pI: 8.15

mw: 50.14 kDa

protein length: 434 aa

gene length: 1302 bp

function: control of ald expression

product: transcription activator (PucR family)

essential: no

synonyms: yukF

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.7|Utilization of alanine/ serine]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]

Gene

Coordinates: 3,276,955 → 3,278,223

Phenotypes of a mutant

• [SW|sporulation] defect due to lack of ''[gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald]'' expression [Pubmed|22797752]

The protein

Catalyzed reaction/ biological activity

• transcription activation of ''[gene|2D346CF412BA32EE18111DA930CFA1306F95024B|ald]'' gene expression in the presence of alanine [Pubmed|22797752]

Protein family

• [SW|PucR family]

Modification

• phosphorylated on Ser-395 [Pubmed|20509597]

Effectors of protein activity

• L-alanine [Pubmed|22797752]

Expression and Regulation

Operons

• genes: [gene|A987E1510578E8DE822C2019488D457CB7CFBE73|adeR]
  description: [Pubmed|8226620]

  regulation

  • constitutively expressed [Pubmed|22797752]

Biological materials

Mutant

• MGNA-A631 (yukF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/631 NBRP B. subtilis, Japan]

References

• 8226620,20509597,22797752