yqfB

resistence protein (against sublancin), accessory role in resistance to cefuroxime

locus: BSU_25370

pI: 11.17

mw: 15.60 kDa

protein length: 139 aa

gene length: 420 bp

function: resistance against sublancin

product: resistence protein (against sublancin)

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 2,617,005 2,617,424

The protein

[SW|Localization]

• cell membrane [Pubmed|22753055]

Expression and Regulation

Operons

• genes: [gene|F6B0D27B434D81B7A680555E4457F266B6206B7D|yqeZ]-[gene|11A55829B4C3E8EA434A600FF7B4102F8E5A7DCE|floA]-[gene|A80317C3B8DF06E2187E02A05C13845508C18B40|yqfB]
  description: [Pubmed|11866510]

  sigma factors

  • [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|11866510], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon]

  regulation

  • expressed under stress conditions ([protein|search|SigW]) [Pubmed|11866510]

Biological materials

Mutant

• MGNA-C453 (yqfB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2451 NBRP B. subtilis, Japan]
• BKE25370 ([gene|A80317C3B8DF06E2187E02A05C13845508C18B40|yqfB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE25370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAGCGTTCTCCCTTCTT, downstream forward: _UP4_TAAAGTGTTAGAACCTCCTT
• BKK25370 ([gene|A80317C3B8DF06E2187E02A05C13845508C18B40|yqfB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK25370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAGCGTTCTCCCTTCTT, downstream forward: _UP4_TAAAGTGTTAGAACCTCCTT

References

• 16629676,11866510,22753055