SubtiBank SubtiBank
scoA [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

scoA [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

succinyl CoA:3-oxoacid CoA-transferase (subunit A)
locus
BSU38990
pI
6.00
mw
25.00 kDa
function
3-hydroxybutyrate utilization
product
succinyl CoA:3-oxoacid CoA-transferase (subunit A)
essential
no
ec
2.8.3.5
synonyms
yxjD

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.1|Utilization of lipids] → [category|SW 2.4.1.3|Utilization of fatty acids]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|SigE regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    4,001,976 -> 4,002,692

    The protein

    Catalyzed reaction/ biological activity

  • Succinyl-CoA a 3-oxo acid = succinate a 3-oxoacyl-CoA (according to Swiss-Prot)
  • Protein family

  • 3-oxoacid CoA-transferase subunit A family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|YodS]
  • Structure

  • [PDB|3CDK] (the [SW|ScoA]-[SW|ScoB] complex)
  • [SW|Interactions]

  • [SW|ScoA]-[SW|ScoB] [Pubmed|17363272]
  • Expression and Regulation

    Operon

  • ''[protein|search|hbuT]-[protein|search|scoA]-[protein|search|scoB]-[protein|search|yxjF]'' [Pubmed|10746760]
  • [SW|Sigma factor]

  • [protein|search|SigE] [Pubmed|12662922]
  • Regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|12850135,10666464]
  • expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|12662922]
  • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|12850135,10666464]
  • References

  • 17363272,10746760,16672620,12662922,12850135,10666464