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tatCD [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]
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tatCD [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

component of the TatAD-TatCD twin-arginine translocase
locus
BSU02640
pI
9.00
mw
27.00 kDa
function
TAT protein secretion
product
component of the twin-arginine translocation pathway
essential
no
synonyms
ycbT

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.3|Phosphate metabolism]
  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|phosphate metabolism], [SW|protein secretion], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|PhoP regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    286,048 -> 286,776

    The protein

    Catalyzed reaction/ biological activity

  • translocation of [protein|search|PhoD] [Pubmed|19395490]
  • Protein family

  • tatC family (according to Swiss-Prot)
  • [SW|Localization]

  • cell membrane [Pubmed|19616508]
  • [SW|Interactions]

  • [SW|TatAD]-[SW|TatCD] [Pubmed|19395490]
  • [SW|TatAC]-[SW|TatCD] [Pubmed|22544248]
  • [protein|search|CsbC]-[SW|TatCD] [Pubmed|23180473]
  • Expression and Regulation

    Operon

  • ''[protein|search|phoD]-[SW|tatAD]-[SW|tatCD]'' [Pubmed|22383849]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|10094677]
  • Regulation

  • expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|11007775]
  • Regulatory mechanism

  • [protein|search|PhoP]: transcription activation [Pubmed|11007775]
  • Biological materials

    Mutant

  • MGNA-C038 (ycbT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2036 NBRP B. subtilis, Japan]
  • Labs working on this gene/protein

  • [SW|Oscar Kuipers], University of Groningen, The Netherlands
  • [http://molgen.biol.rug.nl/molgen/index.php Homepage]
  • References

    Reviews

  • 22683878,24140208,25975269,25494301,27121927
  • Original publications

  • 11007775,15554971,22544248,11007775,19383693,19395490,19616508,22383849,10094677,23180473,24236045