SubtiBank SubtiBank
yrhE [2017-8-11 16:0:3]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

yrhE [2017-8-11 16:0:3]

unknown, similar to formate dehydrogenase
locus
BSU27220
pI
5.16
mw
108.57 kDa
protein length
980 aa Sequence Blast
gene length
2940 bp Sequence Blast
function
unknown
product
unknown
essential
no
ec
1.2.1.2
synonyms

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]
  • Gene

    Coordinates
    2,781,209 → 2,784,151

    The protein

    Catalyzed reaction/ biological activity

  • Formate + NAD+ = CO2 + NADH (according to Swiss-Prot)
  • [SW|Cofactors]

  • contains an iron-sulfur cluster
  • Additional information

  • The gene is annotated in KEGG as an ortholog of formate dehydrogenase EC 1.2.1.2. In Swiss-Prot the protein is named “formate dehydrogenase chain A”. In MetaCyc the protein is characterized as “similar to formate dehydrogenase”. No literature/experimental evidence supporting the annotation is available. [Pubmed|19935659]
  • Expression and Regulation

    Operons

    genes
    [gene|A4304213CFC152B601B2EED2B9B3A0A3AB4E6A81|yrhE]-[gene|364BC3B51D8DF152C2DF31046D4F80595C75884B|yrhD]
    description
    [Pubmed|21815947]

    additional information

  • term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of ''yrhE'' [Pubmed|27120414]
  • view in new tab

    Biological materials

    Mutant

  • MGNA-A160 (yrhE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/160 NBRP B. subtilis, Japan]
  • References

  • 21815947,27120414,19935659