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srtN [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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srtN [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

protein deacetylase for the control of AcsA activity
locus
BSU09650
pI
5.00
mw
27.00 kDa
function
control of AcsA activity
product
NAD( )-dependent AcsA deacetylase
essential
no
synonyms
yhdZ

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.5|Protein acetylases/ deacetylases]
  • [SW|Categories] containing this gene/protein

  • [SW|protein modification]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,040,094 -> 1,040,837

    The protein

    Catalyzed reaction/ biological activity

  • NAD an acetylprotein = nicotinamide O-acetyl-ADP-ribose a protein (according to Swiss-Prot) deacetylates (and thereby activates) [protein|search|AcsA] (together with [protein|search|AcuC]) [Pubmed|19136592]
  • Protein family

  • deacetylase sirtuin-type domain (according to Swiss-Prot)
  • Structure

  • [PDB|1MA3] (from ''Archaeoglobus fulgidus'', 40% identity) [Pubmed|12408821]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • Biological materials

    Mutant

  • GP1210 (''[protein|search|srtN]''::''cat''), available in [SW|Jörg Stülke]'s lab
  • 1A888 ( ''srtN''::''spec''), [Pubmed|19136592], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A888&Search=1A888 BGSC]
  • References

  • 19136592,26708127,12408821,26098117