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ynbA [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]
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ynbA [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

GTP-binding protein, ribosome-splitting factor, rescues translationally arrested ribosomes
locus
BSU17430
pI
9.00
mw
37.00 kDa
function
rescuing of translationally arrested ribosomes
product
GTP-binding protein, ribosome-splitting factor
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.5|Targets of second messengers] → [category|SW 3.5.3|Targets of (p)ppGpp]
  • [category|SW 6|Groups of genes] → [category|SW 6.3|GTP-binding proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|GTP-binding proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,875,304 -> 1,876,566

    The protein

    Catalyzed reaction/ biological activity

  • binds and hydrolyzes GTP and readily exchanges GDP for GTP
  • rescuing of translationally arrested ribosomes [Pubmed|26458047]
  • Protein family

  • GTP1/OBG family (according to Swiss-Prot) Era/Obg family
  • Paralogous protein(s)

  • [protein|search|Era], [protein|search|Obg], [protein|search|YphC], [protein|search|YsxC], [protein|search|RbgA], [protein|search|YqeH], [protein|search|ThdF], [protein|search|YyaF], [protein|search|YnbA]
  • Effectors of protein activity

  • binds ppGpp [Pubmed|26951678], ppGpp may inhibit activity [Pubmed|26951678]
  • Structure

  • [PDB|5ADY] (the protein from ''E. coli'' in complex with the [SW|ribosome], 41% identity) [Pubmed|26458047]
  • Labs working on this gene/protein

  • [SW|Naotake Ogasawara], Nara, Japan
  • References

    Reviews

  • 21885683
  • Original publications

  • 12427945,26458047,26951678,26951678