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rocC [Mon May 16 2016 17:50:13 GMT+0200 (CEST)]
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rocC [Mon May 16 2016 17:50:13 GMT+0200 (CEST)]

amino acid permease
locus
BSU37760
pI
8.00
mw
51.00 kDa
function
arginine, ornithine and citrulline uptake
product
amino acid permease
essential
no
synonyms
ipa-78d

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.4|APC superfamily]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.4|Biosynthesis/ acquisition of arginine]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.4|Utilization of arginine/ ornithine]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|biosynthesis/ acquisition of amino acids], [SW|utilization of amino acids], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AhrC regulon], [SW|CodY regulon], [SW|RocR regulon], [SW|SigL regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,875,780 -> 3,877,192

    The protein

    Paralogous protein(s)

  • [protein|search|AapA], [protein|search|GabP], [protein|search|HutM], [protein|search|RocE], [protein|search|YbgF], [protein|search|YbxG], [protein|search|YdgF], [protein|search|YtnA], [protein|search|YvbW]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|rocA]-[protein|search|rocB]-[protein|search|rocC]'' [Pubmed|8113162]
  • [SW|Sigma factor]

  • [protein|search|SigL] [Pubmed|8113162]
  • Regulation

  • induction by arginine ([protein|search|RocR], [protein|search|AhrC]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8113162,7565595 PubMed]
  • repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|12618455]
  • Regulatory mechanism

  • [protein|search|CodY]: transcription repression [Pubmed|12618455]
  • [protein|search|RocR]: transcription activation [Pubmed|8113162]
  • [protein|search|AhrC]: transcription activation [Pubmed|7565595]
  • References

  • 12618455,8113162,7565595