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dctS [Mon Aug 31 2015 13:52:33 GMT+0200 (CEST)]
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dctS [Mon Aug 31 2015 13:52:33 GMT+0200 (CEST)]

two-component sensor kinase, regulation of the dctS-dctR-dctP operon
locus
BSU04450
pI
6.20
mw
59.00 kDa
function
regulation of the dctS-dctR-dctP operon
product
two-component sensor kinase
essential
no
synonyms
ydbF

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.1|Utilization of organic acids]
  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]
  • syns
    ydbF

    [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources], [SW|protein modification], [SW|transcription factors and their control], [SW|membrane proteins], [SW|phosphoproteins]
  • The protein

    Catalyzed reaction/ biological activity

  • autophosphorylation, phosphorylation of [protein|search|DctR]
  • [SW|Domains]

  • two transmembrane segments
  • [SW|PAS domain]
  • C-terminal histidine phosphotransferase domain
  • Modification

  • autophosphorylation on a His residue
  • Effectors of protein activity

  • [protein|search|DctB] and [protein|search|DctP] act as co-sensors with [protein|search|DctS] [Pubmed|24375102]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|DctS]-[protein|search|DctR]
  • [protein|search|DctB]-[protein|search|DctS]-[protein|search|DctP], sensing complex [Pubmed|24375102]
  • Expression and Regulation

    Operon

  • ''[protein|search|dctS]-[protein|search|dctR]-[protein|search|dctP]'' [Pubmed|10708364]
  • Biological materials

    Mutant

  • GP225 (''dctS''::''cat''), available in [SW|Jörg Stülke]'s lab
  • References

  • 10094672,10708364,24375102