ykkE [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

formyltetrahydrofolate deformylase

locus: BSU13110

pI: 5.00

mw: 34.00 kDa

function: purine nucleotide synthesis

product: formyltetrahydrofolate deformylase

essential: no

ec: 3.5.1.10

synonyms: purU

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.1|Biosynthesis/ acquisition of purine nucleotides]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of nucleotides]

Gene

Coordinates on the chromosome (coding sequence): 1,377,243 -> 1,378,145

The protein

Catalyzed reaction/ biological activity

• 10-formyltetrahydrofolate H₂O = formate tetrahydrofolate (according to Swiss-Prot)

Protein family

• ACT domain (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|PurN]

Structure

• [PDB|3W7B] (from ''Thermus thermophilus'', 58% identity) [Pubmed|24108189]

Expression and Regulation

Operon

• ''[SW|ykkE]'' [Pubmed|22383849]

References

• 24108189,22383849