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yxaB
general stress protein, similar to pyruvyl transferase
function
biofilm formation, survival of salt and ethanol stress
product
putative exopolysaccaride synthase
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation][category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation] → [category|SW 4.1.2.5|Other proteins required for biofilm formation][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)][category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]Gene
Coordinates
4,110,949 4,111,980
The protein
Protein family
polysaccharide pyruvyl transferase family (with [protein|6EBD8F7065B6C1996067F3120DD9CFEA91D3A444|EpsI] and [protein|52A47B49B1FB955EE7E3C316B57A2B4134F78480|EpsO], according to UniProt)Paralogous protein(s)
[protein|6EBD8F7065B6C1996067F3120DD9CFEA91D3A444|EpsI] Structure
[PDB|5AX7] (from yeast, 30% identity) [pubmed|27194449]Expression and Regulation
Operons
genes
[gene|4907D4585491349E2592B0EF9150312A80785EE5|yxaA]-[gene|9A223AE85131511B7EA3A71EA57D87E8B167FA67|yxaB]
description
[Pubmed|15805528,10746760]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|15805528], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon][protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|15805528,18326573], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]regulation
induced by stress ([protein|search|SigB]) [Pubmed|15805528]view in new tabgenes
[gene|9A223AE85131511B7EA3A71EA57D87E8B167FA67|yxaB]
description
[Pubmed|15805528]
regulation
induced by stress ([protein|search|SigB]) [Pubmed|15805528]view in new tabBiological materials
Mutant
MGNA-B681 (yxaB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1680 NBRP B. subtilis, Japan]BKE40030 ([gene|9A223AE85131511B7EA3A71EA57D87E8B167FA67|yxaB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE40030 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCTGCGTCCTCCTTCT, downstream forward: _UP4_TAAACGAAAAAGACTGCCCTBKK40030 ([gene|9A223AE85131511B7EA3A71EA57D87E8B167FA67|yxaB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK40030 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCTGCGTCCTCCTTCT, downstream forward: _UP4_TAAACGAAAAAGACTGCCCTReferences
10746760,15805528,27194449