aminotransferase involved in bacilysin synthesis
function
biosynthesis of the antibiotic bacilysin
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.1|Biosynthesis of antibacterial compounds][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.15|Biosynthesis of antibacterial compounds][SW|Categories] containing this gene/protein
[SW|miscellaneous metabolic pathways], [SW|biosynthesis of antibacterial compounds]This gene is a member of the following [SW|regulons]
[SW|AbrB regulon], [SW|CodY regulon], [SW|ScoC regulon]Gene
Coordinates on the chromosome (coding sequence)
3,868,287 -> 3,869,486
The protein
Catalyzed reaction/ biological activity
YwfG catalyzes transamination of tetrahydro-4-hydroxyphenylpyruvate (with L-Phe as amino donor), to form tetrahydrotyrosine [Pubmed|20052993]Protein family
class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)[SW|Localization]
cytoplasm (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|bacA]-[protein|search|bacB]-[protein|search|bacC]-[protein|search|bacD]-[protein|search|bacE]-[protein|search|bacF]'' [Pubmed|12372825][SW|Sigma factor]
[protein|search|SigA] [Pubmed|19801406]Regulatory mechanism
[protein|search|CodY]: transcription repression [Pubmed|12372825,21709425][protein|search|AbrB]: transcription repression [Pubmed|12697329,21709425][protein|search|ScoC]: transcription repression [Pubmed|19801406]References
12372825,19801406,20052993,21948839,12697329,21709425 
