bsaA

similar to glutathione peroxidase

locus: BSU_21900

pI: 5.25

mw: 18.11 kDa

protein length: 160 aa

gene length: 483 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

Gene

Coordinates: 2,304,553 2,305,035

The protein

Protein family

• glutathione peroxidase family (single member, according to UniProt)

Structure

• [PDB|2WGR] (Schistosoma mansoni phospholipid glutathione peroxidase, 49% identity) [pubmed|19714775]

Additional information

• The gene is annotated in KEGG as glutathione peroxidase EC 1.11.1.9. It is marked in Swiss-Prot as glutathione peroxidase homolog and in MetaCyc as glutathione peroxidase. Several studies suggested that glutathione is probably absent in ''B. subtilis''. [Pubmed|19935659]

Expression and Regulation

Operons

• genes: [gene|9929712AC9E5581DD0EF3213CC49A0E6C8D3087D|bsaA]-[gene|A0CC440185318F7F8665AF7A8279C79A09E35518|ypgQ]-[gene|B42367583867799BD88D737C848E16B9143C5957|ypgR]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A887 (bsaA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/887 NBRP B. subtilis, Japan]
• BKE21900 ([gene|9929712AC9E5581DD0EF3213CC49A0E6C8D3087D|bsaA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTAAGTCCCTCCTATGT, downstream forward: _UP4_GAGCAATAAAAAGAGGGTGT
• BKK21900 ([gene|9929712AC9E5581DD0EF3213CC49A0E6C8D3087D|bsaA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTAAGTCCCTCCTATGT, downstream forward: _UP4_GAGCAATAAAAAGAGGGTGT

References

• 8969496,19935659,19714775