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trpP [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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trpP [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

S protein of tryptophan ECF transporter
locus
BSU10010
pI
11.16
mw
18.00 kDa
function
tryptophan uptake
product
S protein of tryptophan ECF transporter
essential
no
synonyms
yhaG

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.3|ECF transporter]
  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.3|ECF transporter] → [category|SW 1.2.3.2|The substrate-specific S components of the ECF transporters]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.13|Biosynthesis/ acquisition of aromatic amino acids]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|ECF transporter], [SW|biosynthesis/ acquisition of amino acids], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|TRAP regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,074,646 -> 1,075,164

    The protein

    Protein family

  • trpP transporter family (according to Swiss-Prot)
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|YbaF]-[protein|search|TrpP] [Pubmed|20497229]
  • Expression and Regulation

    Operon

  • ''[protein|search|trpP]'' [Pubmed|10735881]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|10735881]
  • Regulation

  • induced in the absence of tryptophan ([protein|search|MtrB]) [Pubmed|10735881]
  • Regulatory mechanism

  • [protein|search|MtrB]: translation inhibition at an [SW|RNA switch], the [protein|search|MtrB] binding site overlaps the Shine-DAlgarno sequence and translation initation region, [protein|search|MtrB] binds in the presence of tryptophan [Pubmed|10735881]
  • References

    Reviews

  • 20497229,22574898,24362466
  • Original publications

  • 10735881,14702295