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yknZ [2018-05-04 18:00:36]
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yknZ [2018-05-04 18:00:36]

ABC transporter (permease) for the export of the SdpC toxin
locus
BSU14370
pI
4.68
mw
41.96 kDa
protein length
397 aa Sequence Blast
gene length
1191 bp Sequence Blast
function
resistence against SdpC toxin
product
ABC transporter (permease)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.3|Export of peptides]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    1,506,105 → 1,507,298

    The protein

    Protein family

  • ABC-4 integral membrane protein family (according to Swiss-Prot)
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    genes
    [gene|70D7098BEBD5E53B4B9B8C3394FAAF972C65EE22|yknU]-[gene|C6B0ACB9D9703DD8141FD7D9D62DB22FB48F458B|yknV]-[gene|916419C4ED113778488EBC558A35810498028B02|yknW]-[gene|FD270195901B89DAAAD134DB9DE729670A9BDECF|yknX]-[gene|FE3A01BEA974C5E32C68DC600C800E5EF101B34F|yknY]-[gene|9680326BAA94A503E2A5C6F0A2479AE0B0467B4C|yknZ]
    description
    [Pubmed|22383849]
    view in new tab

    genes
    [gene|916419C4ED113778488EBC558A35810498028B02|yknW]-[gene|FD270195901B89DAAAD134DB9DE729670A9BDECF|yknX]-[gene|FE3A01BEA974C5E32C68DC600C800E5EF101B34F|yknY]-[gene|9680326BAA94A503E2A5C6F0A2479AE0B0467B4C|yknZ]
    description
    [Pubmed|9987136]

    sigma factors

  • [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|9987136], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon]
  • regulatory mechanism

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|12076816], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]
  • regulation

  • repressed during logrithmic growth ([protein|search|AbrB]) [Pubmed|12076816]
  • view in new tab

    Biological materials

    Mutant

  • MGNA-B351 (yknZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1350 NBRP B. subtilis, Japan]
  • BKE14370 (Δ[gene|9680326BAA94A503E2A5C6F0A2479AE0B0467B4C|yknZ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTGATGTTTTCCAACA, downstream forward: _UP4_TAGCCTCATGCAACATGCAT
  • BKK14370 (Δ[gene|9680326BAA94A503E2A5C6F0A2479AE0B0467B4C|yknZ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTGATGTTTTCCAACA, downstream forward: _UP4_TAGCCTCATGCAACATGCAT
  • References

  • 10092453,16629676,9987136,12076816