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spoVB
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spoVB

MurJ family lipid II flippase, spore cortex peptidoglycan synthesis
locus
BSU_27670
pI
10.19
mw
55.91 kDa
protein length
518 aa Sequence Blast
gene length
1557 bp Sequence Blast
function
spore cortex peptidoglycan synthesis
product
sporulation-specific MurJ family lipid II flippase
essential
no
synonyms
spoIIIF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    2,829,564 2,831,120

    The protein

    Protein family

  • [SW|Polysaccharide synthase family] (according to UniProt)
  • [SW|MOP exporter family]

    • Paralogous protein(s)

  • [protein|D6B1837075ECBEE1FEAC704DDB6795336092897F|YabM], [protein|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|MurJ], [protein|34A5CD28A3DBCB10B4E1C82E50143FA73B553919|YkvU]

    • [SW|Localization]

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]-[gene|C52461A2FE856C94E0D0701FB7412368404FC83B|yrzE]
    description
    [pubmed|22383849]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [pubmed|1744050], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

    • regulatory mechanism

  • [protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID]: repression, [pubmed|15383836], in [regulon|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID regulon]

    • regulation

  • expressed early during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE], [SW|SpoIIID]) [Pubmed|1744050,15383836]
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    Biological materials

    Mutant

  • BKE27670 ([gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTACCCCCTGCCTTC, downstream forward: _UP4_GGACGGTTGATCATCCGATA
  • BKK27670 ([gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTACCCCCTGCCTTC, downstream forward: _UP4_GGACGGTTGATCATCCGATA

    • References

  • 19648239,19666716,1744050,15383836,25918422