SubtiBank SubtiBank
htpG
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htpG

class III heat-shock protein (molecular chaperone)
locus
BSU_39820
pI
4.67
mw
72.08 kDa
protein length
626 aa Sequence Blast
gene length
1881 bp Sequence Blast
function
chaperone
product
class III heat-shock protein (molecular chaperone)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.2|Chaperones/ protein folding]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.4|Heat shock proteins]
  • Gene

    Coordinates
    4,089,429 4,091,309

    The protein

    Protein family

  • heat shock protein 90 family (single member, according to UniProt)
  • Structure

  • [PDB|2IOQ] (from ''Escherichia coli'', 39% identity, 61% similarity) [Pubmed|17055434]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    genes
    [gene|962A955DED82EC0197757206A706796EC8F768BD|htpG]
    description
    [Pubmed|9150201]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|9150201], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • regulation

  • induced by high temperature [Pubmed|9150201]
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    Biological materials

    Mutant

  • GP1159 (del cat) available in [SW|Jörg Stülke]'s lab
  • BKE39820 ([gene|962A955DED82EC0197757206A706796EC8F768BD|htpG]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTCTTGATCGCTCCTTTA, downstream forward: _UP4_TAAACAGAAAAAGGAATCGT
  • BKK39820 ([gene|962A955DED82EC0197757206A706796EC8F768BD|htpG]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTCTTGATCGCTCCTTTA, downstream forward: _UP4_TAAACAGAAAAAGGAATCGT
  • References

  • 9150201,12511492,10323241