csbD

general stress protein

locus: BSU_36670

pI: 9.69

mw: 6.66 kDa

protein length: 62 aa

gene length: 189 bp

function: survival of salt stress and at low temperatures

product: unknown

essential: no

synonyms: ywmG

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]

Gene

Coordinates: 3,770,104 3,770,292

The protein

Protein family

• UPF0337 (CsbD) family (single member, according to UniProt)

Expression and Regulation

Operons

• genes: [gene|958B606BFE4C3A3E1A48787A8F427CCCDCB65422|csbD]
  description: [Pubmed|10376822]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|10376822,15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

  regulation

  • ''csbD'': induced by stress ([protein|search|SigB]) [Pubmed|10376822,15805528]

• genes: [gene|F775A9E74554ECBB7DD6F905FB95D67B848CBF21|ywmF]-[gene|958B606BFE4C3A3E1A48787A8F427CCCDCB65422|csbD]
  description: [Pubmed|10376822]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

  regulation

  • ''csbD'': induced by stress ([protein|search|SigB]) [Pubmed|10376822,15805528]

Biological materials

Mutant

• MGNA-A194 (ywmG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/194 NBRP B. subtilis, Japan]
• BKE36670 ([gene|958B606BFE4C3A3E1A48787A8F427CCCDCB65422|csbD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAATTCTCCCCTCTC, downstream forward: _UP4_TAATCGTACGGAAGAGGCAG
• BKK36670 ([gene|958B606BFE4C3A3E1A48787A8F427CCCDCB65422|csbD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAATTCTCCCCTCTC, downstream forward: _UP4_TAATCGTACGGAAGAGGCAG

References

• 10376822,15805528