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spsJ [Wed Dec 02 2015 19:44:31 GMT+0100 (CET)]
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spsJ [Wed Dec 02 2015 19:44:31 GMT+0100 (CET)]

dTDP -glucose-4,6-dehydratase, spore coat polysaccharide synthesis
locus
BSU37830
pI
6.00
mw
35.00 kDa
function
rhamnose biosynthesis, spore coat polysaccharide synthesis
product
dTDP -glucose-4,6-dehydratase
essential
no
ec
4.2.1.46
synonyms
ipa-72d

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.7|Biosynthesis of rhamnose (for the exosporium)]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|miscellaneous metabolic pathways], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|GerE regulon], [SW|SigK regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,884,292 -> 3,885,239

    The protein

    Catalyzed reaction/ biological activity

  • dTDP-glucose --> dTDP-4-dehydro-6-deoxyglucose [Pubmed|22960854]
  • Protein family

  • sugar epimerase family (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|spsA]-[protein|search|spsB]-[protein|search|spsC]-[protein|search|spsD]-[protein|search|spsE]-[protein|search|spsF]-[protein|search|spsG]-[protein|search|spsI]-[protein|search|spsJ]-[protein|search|spsK]-[protein|search|spsL]'' [Pubmed|9353933]
  • [SW|Sigma factor]

  • [protein|search|SigK] [Pubmed|15383836]
  • Regulation

  • expressed late during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|25239894,15383836]
  • Regulatory mechanism

  • [protein|search|GerE]: transcription activation [Pubmed|25239894,15383836]
  • References

  • 9353933,15383836,22960854,25239894