SubtiBank SubtiBank
ykuL [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]
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ykuL [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

unknown
locus
BSU14130
pI
5.00
mw
16.00 kDa
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.5|Targets of second messengers] → [category|SW 3.5.1|Targets of c-di-AMP]
  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

    • [SW|Categories] containing this gene/protein

  • [SW|proteins of unknown function]

    • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|Spo0A regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,485,453 -> 1,485,896

    The protein

    [SW|Domains]

  • [SW|CBS domain] (18-78)

    • Structure

  • [PDB|1YAV]

    • Expression and Regulation

    Operon

  • ''[protein|search|ykuJ]-[protein|search|ykuK]-[protein|search|abbA]-[protein|search|ykuL]-[protein|search|ccpC]'' [Pubmed|16395550]

    • Regulation

  • expressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]

    • Regulatory mechanism

  • [SW|Spo0A]: transcription activation [Pubmed|14651647]
  • [protein|search|CcpA]: transcription repression [Pubmed|16395550]

    • Biological materials

    Mutant

  • GP214 (deletion of ''[protein|search|ykuJ]-[protein|search|ykuK]-[protein|search|abbA]-[protein|search|ykuL]'', replaced by ''aphA3''), available in the [SW|Stülke] lab

    • Expression vector

  • pGP2929 (N-terminal His-tag, purification from ''E. coli'', in [SW|pWH844]), available in [SW|Jörg Stülke]'s lab

    • References

  • 14651647,16395550