SubtiBank SubtiBank
acpA
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acpA

acyl carrier protein
locus
BSU15920
pI
3.59
mw
8.45 kDa
protein length
gene length
231 bp Sequence Blast
function
fatty acid biosynthesis
product
acyl carrier protein
essential
yes
synonyms
acpP

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.1|Biosynthesis of fatty acids]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • Gene

    Coordinates
    1,665,337 → 1,665,570

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Structure

  • [PDB|1F80] (complex with [protein|200BE4802FCE3C860565B374EAADC9C1FEEF3E49|AcpS]) [Pubmed|10997907], [PDB|3EJE] (complex with [protein|8FBC9A1AC108DC99E275D7A27C18C797D3CDB936|BioI]) [Pubmed|18838690], [PDB|1HY8]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot), during sporulation in the mother cell [Pubmed|19850612]
  • Expression and Regulation

    Operons

    genes
    [gene|8D260693D0C69442BCB9F3D8480E8425ACFE34D2|acpA]
    description
    [Pubmed|19850612]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|16932747], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • regulatory mechanism

  • [protein|FCDE900167AE36377979E0CF7BC33C7F351B95D3|FapR]: repression, [Pubmed|12737802], in [regulon|FCDE900167AE36377979E0CF7BC33C7F351B95D3|FapR regulon]
  • view in new tab

    genes
    [gene|FCDE900167AE36377979E0CF7BC33C7F351B95D3|fapR]-[gene|8F5612395EBF90BEF4C80056EECAFC572384E7F8|plsX]-[gene|BB8542A6444564B21FF5DB6E2C75192C6DA2DFB8|fabD]-[gene|439B468A13137000FB42E9389391CB4986FFED84|fabG]-[gene|8D260693D0C69442BCB9F3D8480E8425ACFE34D2|acpA]
    description
    [Pubmed|19850612]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|16932747], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • regulatory mechanism

  • [protein|FCDE900167AE36377979E0CF7BC33C7F351B95D3|FapR]: repression, [Pubmed|12737802], in [regulon|FCDE900167AE36377979E0CF7BC33C7F351B95D3|FapR regulon]
  • [protein|7832489F11F606BCF637EC23BAAB41AD10237EBB|ComA]: activation, ([protein|7832489F11F606BCF637EC23BAAB41AD10237EBB|ComA]) [Pubmed|16091051], in [regulon|7832489F11F606BCF637EC23BAAB41AD10237EBB|ComA regulon]
  • regulation

  • ''[protein|FCDE900167AE36377979E0CF7BC33C7F351B95D3|FapR]'': repressed in the absence of malonyl-CoA or malonyl-[protein|8D260693D0C69442BCB9F3D8480E8425ACFE34D2|ACP] ([protein|FCDE900167AE36377979E0CF7BC33C7F351B95D3|FapR]) [Pubmed|12737802]
  • view in new tab

    Labs working on this gene/protein

  • [SW|Diego de Mendoza], Universidad Nacional de Rosario, Argentine [http://www.ibr.gov.ar/eng/investigacion/demendoza.htm homepage]
  • References

    Reviews

  • 15952903,20658980
  • Original Publications

  • 10997907,19850612,12737802,18838690,20201588,23033921