ftsW [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

SEDS family peptidoglycan glycosyltransferase, cell-division protein

Locus: BSU14850

Isoelectric point: 9.00

Molecular weight: 43.00 kDa

Function: cell division

Product: SEDS family peptidoglycan glycosyltransferase

Essential: yes

Synonyms: ylaO

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Cell envelope and cell division → Cell division → Other genes
• Groups of genes → Essential genes
• Groups of genes → Membrane proteins

Categories containing this gene/protein

• cell division, essential genes, membrane proteins

This gene is a member of the following regulons

• YofA regulon

Gene

Coordinates on the chromosome (coding sequence): 1,552,899 -> 1,554,110

Phenotypes of a mutant

• essential PubMed

The protein

Catalyzed reaction/ biological activity

• principal peptidoglycan glycosyltransferase of the divisome PubMed

Protein family

• FtsW/RodA/SpoVE family (according to Swiss-Prot)
• SEDS proteins (shape, elongation, division, and sporulation) PubMed

Paralogous protein(s)

• RodA, SpoVE

Localization

• integral membrane protein
• localization depends on FtsZ 26679002

Interactions

• Maf-FtsW PubMed
• may be part of the divisome 26679002

Expression and Regulation

Operon

• ftsW-pycA (according to DBTBS)

Regulation

• constitutively expressed PubMed

Regulatory mechanism

• YofA: transcription activation PubMed

Biological materials

FLAG-tag construct

• GP2007 ftsW-3xFLAG ermC (based on pGP1087), available in Jörg Stülke's lab

References

Reviews

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Original Publications

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