glucose-1-phosphate thymidylyltransferase, spore coat polysaccharide synthesis
function
rhamnose biosynthesis, spore coat polysaccharide synthesis
product
glucose-1-phosphate thymidylyltransferase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.7|Biosynthesis of rhamnose (for the exosporium)][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][SW|Categories] containing this gene/protein
[SW|miscellaneous metabolic pathways], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|GerE regulon], [SW|SigE regulon], [SW|SigK regulon]Gene
Coordinates on the chromosome (coding sequence)
3,885,239 -> 3,885,979
The protein
Catalyzed reaction/ biological activity
alpha-D-glucose-1-phosphate dTTP --> dTDP-glucose [Pubmed|22960854]Protein family
glucose-1-phosphate thymidylyltransferase family (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|spsA]-[protein|search|spsB]-[protein|search|spsC]-[protein|search|spsD]-[protein|search|spsE]-[protein|search|spsF]-[protein|search|spsG]-[protein|search|spsI]-[protein|search|spsJ]-[protein|search|spsK]-[protein|search|spsL]'' [Pubmed|9353933][SW|Sigma factor]
[SW|SigE] [Pubmed|26577401], [protein|search|SigK] [Pubmed|15383836]Regulation
expressed during [SW|sporulation] in the mother cell ([SW|SigE], [protein|search|SigK], [protein|search|GerE]) [Pubmed|26577401,25239894,15383836]Regulatory mechanism
[protein|search|GerE]: transcription activation [Pubmed|25239894,15383836]Additional information
the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]References
9353933,15383836,12884008,21821766,22960854,25239894,26577401 
