SubtiBank SubtiBank
pbpH [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]
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pbpH [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

class B penicillin-binding protein H, required for cell wall synthesis during cell elongation
locus
BSU13980
pI
8.00
mw
76.00 kDa
function
formation of a rod-shaped peptidoglycan cell wall
product
penicillin-binding protein H
essential
no
synonyms
ykuA

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.7|Penicillin-binding proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|cell wall synthesis], [SW|membrane proteins], [SW|penicillin-binding proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,467,805 -> 1,469,862

    The protein

    Catalyzed reaction/ biological activity

  • required for [SW|cell wall synthesis] during cell elongation [Pubmed|12896990]
  • driver of [protein|search|MreB] dynamics [Pubmed|21636744,21636745]
  • Protein family

  • transpeptidase family (according to Swiss-Prot)
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • localization depends on the availability of peptidoglyan precursors (lipid II) [Pubmed|23895585]
  • [SW|Interactions]

  • part of the [SW|elongasome] [Pubmed|21636744,21636745]
  • Expression and Regulation

    Regulatory mechanism

  • [protein|search|AbrB]: transcription repression [Pubmed|20817675]
  • Additional information

  • A [protein|search|ncRNA] is predicted between '[protein|search|ykwD]' and '[protein|search|pbpH]' [PubMed|20525796]
  • References

  • 12896990,20525796,21636744,21636745,20817675,23199363,23895585